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Positive Signature-Tagged Mutagenesis in Pseudomonas aeruginosa: Tracking Patho-Adaptive Mutations Promoting Airways Chronic Infection

The opportunistic pathogen Pseudomonas aeruginosa can establish life-long chronic infections in the airways of cystic fibrosis (CF) patients. Persistent lifestyle is established with P. aeruginosa patho-adaptive variants, which are clonal with the initially-acquired strains. Several reports indicate...

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Detalles Bibliográficos
Autores principales: Bianconi, Irene, Milani, Andrea, Cigana, Cristina, Paroni, Moira, Levesque, Roger C., Bertoni, Giovanni, Bragonzi, Alessandra
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033382/
https://www.ncbi.nlm.nih.gov/pubmed/21304889
http://dx.doi.org/10.1371/journal.ppat.1001270