The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study

While there have been studies exploring regulatory variation in one or more tissues, the complexity of tissue-specificity in multiple primary tissues is not yet well understood. We explore in depth the role of cis-regulatory variation in three human tissues: lymphoblastoid cell lines (LCL), skin, an...

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Detalles Bibliográficos
Autores principales: Nica, Alexandra C., Parts, Leopold, Glass, Daniel, Nisbet, James, Barrett, Amy, Sekowska, Magdalena, Travers, Mary, Potter, Simon, Grundberg, Elin, Small, Kerrin, Hedman, Åsa K., Bataille, Veronique, Tzenova Bell, Jordana, Surdulescu, Gabriela, Dimas, Antigone S., Ingle, Catherine, Nestle, Frank O., di Meglio, Paola, Min, Josine L., Wilk, Alicja, Hammond, Christopher J., Hassanali, Neelam, Yang, Tsun-Po, Montgomery, Stephen B., O'Rahilly, Steve, Lindgren, Cecilia M., Zondervan, Krina T., Soranzo, Nicole, Barroso, Inês, Durbin, Richard, Ahmadi, Kourosh, Deloukas, Panos, McCarthy, Mark I., Dermitzakis, Emmanouil T., Spector, Timothy D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033383/
https://www.ncbi.nlm.nih.gov/pubmed/21304890
http://dx.doi.org/10.1371/journal.pgen.1002003

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