WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ

The transcriptional co-activators YAP and TAZ are downstream targets inhibited by the Hippo tumor suppressor pathway. YAP and TAZ both possess WW domains, which are important protein–protein interaction modules that mediate interaction with proline-rich motifs, most commonly PPXY. The WW domains of...

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Detalles Bibliográficos
Autores principales: Chan, S W, Lim, C J, Huang, C, Chong, Y F, Gunaratne, H J, Hogue, K A, Blackstock, W P, Harvey, K F, Hong, W
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033532/
https://www.ncbi.nlm.nih.gov/pubmed/20972459
http://dx.doi.org/10.1038/onc.2010.438

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