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CYP2C19 and ABCB1 gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population

BACKGROUND: Recent studies have reported the clinical importance of CYP2C19 and ABCB1 polymorphisms in an individualized approach to clopidogrel treatment. The aims of this study were to evaluate the frequencies of CYP2C19 and ABCB1 polymorphisms and to identify the clopidogrel-predicted metabolic p...

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Detalles Bibliográficos
Autores principales: Santos, Paulo CJL, Soares, Renata AG, Santos, Diogo BG, Nascimento, Raimundo M, Coelho, George LLM, Nicolau, José C, Mill, José G, Krieger, José E, Pereira, Alexandre C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033793/
https://www.ncbi.nlm.nih.gov/pubmed/21247447
http://dx.doi.org/10.1186/1471-2350-12-13