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Next-generation sequencing for HLA typing of class I loci

BACKGROUND: Comprehensive sequence characterization across the MHC is important for successful organ transplantation and genetic association studies. To this end, we have developed an automated sample preparation, molecular barcoding and multiplexing protocol for the amplification and sequence-deter...

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Detalles Bibliográficos
Autores principales: Erlich, Rachel L, Jia, Xiaoming, Anderson, Scott, Banks, Eric, Gao, Xiaojiang, Carrington, Mary, Gupta, Namrata, DePristo, Mark A, Henn, Matthew R, Lennon, Niall J, de Bakker, Paul IW
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033818/
https://www.ncbi.nlm.nih.gov/pubmed/21244689
http://dx.doi.org/10.1186/1471-2164-12-42