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Comparative nucleic acid transfection efficacy in primary hepatocytes for gene silencing and functional studies

BACKGROUND: Primary hepatocytes are the best resource for in vitro studies directed at understanding hepatic processes at the cellular and molecular levels, necessary for novel drug development to treat highly prevalent diseases such as non-alcoholic steatohepatitis, cardiovascular disease and type...

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Detalles Bibliográficos
Autores principales: Park, Jae-Seung, Surendran, Sneha, Kamendulis, Lisa M, Morral, Núria
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033823/
https://www.ncbi.nlm.nih.gov/pubmed/21244687
http://dx.doi.org/10.1186/1756-0500-4-8