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Transient Responses to NOTCH and TLX1/HOX11 Inhibition in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

To improve the treatment strategies of T-cell acute lymphoblastic leukemia/lymphoma (T-ALL), further efforts are needed to identify therapeutic targets. Dysregulated expression of HOX-type transcription factors occurs in 30–40% of cases of T-ALL. TLX1/HOX11 is the prototypical HOX-type transcription...

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Detalles Bibliográficos
Autores principales:	Rakowski, Lesley A., Lehotzky, Erica A., Chiang, Mark Y.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033898/ https://www.ncbi.nlm.nih.gov/pubmed/21326611 http://dx.doi.org/10.1371/journal.pone.0016761

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