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Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the gen...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033904/ https://www.ncbi.nlm.nih.gov/pubmed/21326861 http://dx.doi.org/10.1371/journal.pone.0016896 |
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author | Wu, Beilei Blanchard-Letort, Alexandra Liu, Yan Zhou, Guanghe Wang, Xifeng Elena, Santiago F. |
author_facet | Wu, Beilei Blanchard-Letort, Alexandra Liu, Yan Zhou, Guanghe Wang, Xifeng Elena, Santiago F. |
author_sort | Wu, Beilei |
collection | PubMed |
description | Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the genetic structure of natural BYDV-PAV populations, as well as of the mechanisms maintaining its high diversity, remain poorly explored. In this study, we investigate the dynamics of BYDV-PAV genome evolution utilizing time-structured data sets of complete genomic sequences from 58 isolates from different hosts obtained worldwide. First, we observed that BYDV-PAV exhibits a high frequency of homologous recombination. Second, our analysis revealed that BYDV-PAV genome evolves under purifying selection and at a substitution rate similar to other RNA viruses (3.158×10(−4) nucleotide substitutions/site/year). Phylogeography analyses show that the diversification of BYDV-PAV can be explained by local geographic adaptation as well as by host-driven adaptation. These results increase our understanding of the diversity, molecular evolutionary characteristics and epidemiological properties of an economically important plant RNA virus. |
format | Text |
id | pubmed-3033904 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-30339042011-02-15 Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV Wu, Beilei Blanchard-Letort, Alexandra Liu, Yan Zhou, Guanghe Wang, Xifeng Elena, Santiago F. PLoS One Research Article Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the genetic structure of natural BYDV-PAV populations, as well as of the mechanisms maintaining its high diversity, remain poorly explored. In this study, we investigate the dynamics of BYDV-PAV genome evolution utilizing time-structured data sets of complete genomic sequences from 58 isolates from different hosts obtained worldwide. First, we observed that BYDV-PAV exhibits a high frequency of homologous recombination. Second, our analysis revealed that BYDV-PAV genome evolves under purifying selection and at a substitution rate similar to other RNA viruses (3.158×10(−4) nucleotide substitutions/site/year). Phylogeography analyses show that the diversification of BYDV-PAV can be explained by local geographic adaptation as well as by host-driven adaptation. These results increase our understanding of the diversity, molecular evolutionary characteristics and epidemiological properties of an economically important plant RNA virus. Public Library of Science 2011-02-04 /pmc/articles/PMC3033904/ /pubmed/21326861 http://dx.doi.org/10.1371/journal.pone.0016896 Text en Wu et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Wu, Beilei Blanchard-Letort, Alexandra Liu, Yan Zhou, Guanghe Wang, Xifeng Elena, Santiago F. Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV |
title | Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV |
title_full | Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV |
title_fullStr | Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV |
title_full_unstemmed | Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV |
title_short | Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV |
title_sort | dynamics of molecular evolution and phylogeography of barley yellow dwarf virus-pav |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033904/ https://www.ncbi.nlm.nih.gov/pubmed/21326861 http://dx.doi.org/10.1371/journal.pone.0016896 |
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