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Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV

Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the gen...

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Autores principales: Wu, Beilei, Blanchard-Letort, Alexandra, Liu, Yan, Zhou, Guanghe, Wang, Xifeng, Elena, Santiago F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033904/
https://www.ncbi.nlm.nih.gov/pubmed/21326861
http://dx.doi.org/10.1371/journal.pone.0016896
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author Wu, Beilei
Blanchard-Letort, Alexandra
Liu, Yan
Zhou, Guanghe
Wang, Xifeng
Elena, Santiago F.
author_facet Wu, Beilei
Blanchard-Letort, Alexandra
Liu, Yan
Zhou, Guanghe
Wang, Xifeng
Elena, Santiago F.
author_sort Wu, Beilei
collection PubMed
description Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the genetic structure of natural BYDV-PAV populations, as well as of the mechanisms maintaining its high diversity, remain poorly explored. In this study, we investigate the dynamics of BYDV-PAV genome evolution utilizing time-structured data sets of complete genomic sequences from 58 isolates from different hosts obtained worldwide. First, we observed that BYDV-PAV exhibits a high frequency of homologous recombination. Second, our analysis revealed that BYDV-PAV genome evolves under purifying selection and at a substitution rate similar to other RNA viruses (3.158×10(−4) nucleotide substitutions/site/year). Phylogeography analyses show that the diversification of BYDV-PAV can be explained by local geographic adaptation as well as by host-driven adaptation. These results increase our understanding of the diversity, molecular evolutionary characteristics and epidemiological properties of an economically important plant RNA virus.
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spelling pubmed-30339042011-02-15 Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV Wu, Beilei Blanchard-Letort, Alexandra Liu, Yan Zhou, Guanghe Wang, Xifeng Elena, Santiago F. PLoS One Research Article Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the genetic structure of natural BYDV-PAV populations, as well as of the mechanisms maintaining its high diversity, remain poorly explored. In this study, we investigate the dynamics of BYDV-PAV genome evolution utilizing time-structured data sets of complete genomic sequences from 58 isolates from different hosts obtained worldwide. First, we observed that BYDV-PAV exhibits a high frequency of homologous recombination. Second, our analysis revealed that BYDV-PAV genome evolves under purifying selection and at a substitution rate similar to other RNA viruses (3.158×10(−4) nucleotide substitutions/site/year). Phylogeography analyses show that the diversification of BYDV-PAV can be explained by local geographic adaptation as well as by host-driven adaptation. These results increase our understanding of the diversity, molecular evolutionary characteristics and epidemiological properties of an economically important plant RNA virus. Public Library of Science 2011-02-04 /pmc/articles/PMC3033904/ /pubmed/21326861 http://dx.doi.org/10.1371/journal.pone.0016896 Text en Wu et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Wu, Beilei
Blanchard-Letort, Alexandra
Liu, Yan
Zhou, Guanghe
Wang, Xifeng
Elena, Santiago F.
Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_full Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_fullStr Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_full_unstemmed Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_short Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_sort dynamics of molecular evolution and phylogeography of barley yellow dwarf virus-pav
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033904/
https://www.ncbi.nlm.nih.gov/pubmed/21326861
http://dx.doi.org/10.1371/journal.pone.0016896
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