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SIMPLE/LITAF Expression Induces the Translocation of the Ubiquitin Ligase Itch towards the Lysosomal Compartments

LITAF is a small cellular protein with an unknown function. The C-terminus of LITAF contains a highly conserved domain termed the SIMPLE-like domain (SLD), while the N-terminus contains two PPXY motifs that mediate protein-protein interactions with WW-domain containing proteins. LITAF also harbors t...

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Detalles Bibliográficos
Autores principales:	Eaton, Heather E., Desrochers, Guillaume, Drory, Samuel B., Metcalf, Julie, Angers, Annie, Brunetti, Craig R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033906/ https://www.ncbi.nlm.nih.gov/pubmed/21326863 http://dx.doi.org/10.1371/journal.pone.0016873

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