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Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages
TAL1/SCL is a master regulator of haematopoiesis whose expression promotes opposite outcomes depending on the cell type: differentiation in the erythroid lineage or oncogenesis in the T-cell lineage. Here, we used a combination of ChIP sequencing and gene expression profiling to compare the function...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034015/ https://www.ncbi.nlm.nih.gov/pubmed/21179004 http://dx.doi.org/10.1038/emboj.2010.342 |