A Phase 1/2, Dose-Escalation Trial of Deferasirox for the Treatment of Iron Overload in HFE-Related Hereditary Hemochromatosis

Hereditary hemochromatosis (HH) is characterized by increased intestinal iron absorption that may result in iron overload. Although phlebotomy is widely practiced, it is poorly tolerated or contraindicated in patients with anemias, severe heart disease, or poor venous access, and compliance can vary...

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Detalles Bibliográficos
Autores principales: Phatak, Pradyumna, Brissot, Pierre, Wurster, Mark, Adams, Paul C, Bonkovsky, Herbert L, Gross, John, Malfertheiner, Peter, McLaren, Gordon D, Niederau, Claus, Piperno, Alberto, Powell, Lawrie W, Russo, Mark W, Stoelzel, Ulrich, Stremmel, Wolfgang, Griffel, Louis, Lynch, Nicola, Zhang, Yiyun, Pietrangelo, Antonello
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:
Steatohepatitis/Metabolic Liver Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034044/
https://www.ncbi.nlm.nih.gov/pubmed/20814896
http://dx.doi.org/10.1002/hep.23879

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