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Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?
We have recently reported that progeroid Zmpste24(−/−) mice, which exhibit multiple defects that phenocopy Hutchinson-Gilford progeria syndrome, show a profound dysregulation of somatotropic axis, mainly characterized by the occurrence of very high circulating levels of growth hormone (GH) and a dra...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034170/ https://www.ncbi.nlm.nih.gov/pubmed/21212467 |