Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice

Circadian clock is implicated in the regulation of aging. The transcription factor CLOCK, a core component of the circadian system, operates in complex with another circadian clock protein BMAL1. Recently it was demonstrated that BMAL1 deficiency results in premature aging in mice. Here we investiga...

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Detalles Bibliográficos
Autores principales: Dubrovsky, Yuliya V., Samsa, William E., Kondratov, Roman V.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034182/
https://www.ncbi.nlm.nih.gov/pubmed/21149897

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