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The FACT subunit TbSpt16 is involved in cell cycle specific control of VSG expression sites in Trypanosoma brucei

The African trypanosome Trypanosoma brucei monoallelically expresses one of more than 1000 Variant Surface Glycoprotein (VSG) genes. The active VSG is transcribed from one of about 15 telomeric VSG expression sites (ESs). It is unclear how monoallelic expression of VSG is controlled, and how inactiv...

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Detalles Bibliográficos
Autores principales: Denninger, Viola, Fullbrook, Alexander, Bessat, Mohamed, Ersfeld, Klaus, Rudenko, Gloria
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034197/
https://www.ncbi.nlm.nih.gov/pubmed/20879999
http://dx.doi.org/10.1111/j.1365-2958.2010.07350.x