PKCδ Sensitizes Neuroblastoma Cells to L-Buthionine-Sulfoximine and Etoposide Inducing Reactive Oxygen Species Overproduction and DNA Damage

Neuroblastoma is a type of pediatric cancer. The sensitivity of neuroblastoma (NB) cancer cells to chemotherapy and radiation is inhibited by the presence of antioxidants, such as glutathione (GSH), which is crucial in counteracting the endogenous production of reactive oxygen species (ROS). We have...

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Detalles Bibliográficos
Autores principales: Marengo, Barbara, De Ciucis, Chiara, Ricciarelli, Roberta, Passalacqua, Mario, Nitti, Mariapaola, Zingg, Jean-Marc, Marinari, Umberto M., Pronzato, Maria A., Domenicotti, Cinzia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034714/
https://www.ncbi.nlm.nih.gov/pubmed/21326872
http://dx.doi.org/10.1371/journal.pone.0014661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034714/
https://www.ncbi.nlm.nih.gov/pubmed/21326872
http://dx.doi.org/10.1371/journal.pone.0014661

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