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ATM mediated phosphorylation of CHD4 contributes to genome maintenance

BACKGROUND: In order to maintain cellular viability and genetic integrity cells must respond quickly following the induction of cytotoxic double strand DNA breaks (DSB). This response requires a number of processes including stabilisation of the DSB, signalling of the break and repair. It is becomin...

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Detalles Bibliográficos
Autores principales: Urquhart, Aaron J, Gatei, Magtouf, Richard, Derek J, Khanna, Kum Kum
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035021/
https://www.ncbi.nlm.nih.gov/pubmed/21219611
http://dx.doi.org/10.1186/2041-9414-2-1