A Novel Paclitaxel Microemulsion Containing a Reduced Amount of Cremophor EL: Pharmacokinetics, Biodistribution, and In Vivo Antitumor Efficacy and Safety

The purpose of this study was to prepare a novel paclitaxel (PTX) microemulsion containing a reduced amount of Cremophor EL (CrEL) which had similar pharmacokinetics and antitumor efficacy as the commercially available PTX injection, but a significantly reduced allergic effect due to the CrEL. The p...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Wu, Ke-Chun, Zhao, Bing-Xiang, Zhao, Xin, Wang, Xin, Chen, Su, Nie, Shu-Fang, Pan, Wei-San, Zhang, Xuan, Zhang, Qiang
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035038/
https://www.ncbi.nlm.nih.gov/pubmed/21331356
http://dx.doi.org/10.1155/2011/854872

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