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Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice
Hundreds of small nuclear non-coding RNAs, including small nucleolar RNAs (snoRNAs), have been identified in different organisms, with important implications in regulating gene expression and in human diseases. However, functionalizing these nuclear RNAs in mammalian cells remains challenging, due t...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035437/ https://www.ncbi.nlm.nih.gov/pubmed/21062825 http://dx.doi.org/10.1093/nar/gkq1121 |