Formation of a G-quadruplex at the BCL2 major breakpoint region of the t(14;18) translocation in follicular lymphoma

The t(14;18) translocation in follicular lymphoma is one of the most common chromosomal translocations. Most breaks on chromosome 18 are located at the 3′-UTR of the BCL2 gene and are mainly clustered in the major breakpoint region (MBR). Recently, we found that the BCL2 MBR has a non-B DNA characte...

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Detalles Bibliográficos
Autores principales: Nambiar, Mridula, Goldsmith, G., Moorthy, Balaji T., Lieber, Michael R., Joshi, Mamata V., Choudhary, Bibha, Hosur, Ramakrishna V., Raghavan, Sathees C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035451/
https://www.ncbi.nlm.nih.gov/pubmed/20880994
http://dx.doi.org/10.1093/nar/gkq824

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