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Photosensitized [2 + 2] cycloaddition of N-acetylated cytosine affords stereoselective formation of cyclobutane pyrimidine dimer
Photocycloaddition between two adjacent bases in DNA produces a cyclobutane pyrimidine dimer (CPD), which is one of the major UV-induced DNA lesions, with either the cis-syn or trans-syn structure. In this study, we investigated the photosensitized intramolecular cycloaddition of partially-protected...
Autores principales: | Yamamoto, Junpei, Nishiguchi, Kosuke, Manabe, Koichiro, Masutani, Chikahide, Hanaoka, Fumio, Iwai, Shigenori |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035463/ https://www.ncbi.nlm.nih.gov/pubmed/20880992 http://dx.doi.org/10.1093/nar/gkq855 |
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