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Neuromuscular Junction Defects in Mice with Mutation of dynein heavy chain 1
Disruptions in axonal transport have been implicated in a wide range of neurodegenerative diseases. Cramping 1 (Cra1/+) and Legs at odd angles (Loa/+) mice, with hypomorphic mutations in the dynein heavy chain 1 gene, which encodes the ATPase of the retrograde motor protein dynein, were originally r...
Autores principales: | Courchesne, Stephanie L., Pazyra-Murphy, Maria F., Lee, Daniel J., Segal, Rosalind A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035627/ https://www.ncbi.nlm.nih.gov/pubmed/21346813 http://dx.doi.org/10.1371/journal.pone.0016753 |
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