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Neuromuscular Junction Defects in Mice with Mutation of dynein heavy chain 1

Disruptions in axonal transport have been implicated in a wide range of neurodegenerative diseases. Cramping 1 (Cra1/+) and Legs at odd angles (Loa/+) mice, with hypomorphic mutations in the dynein heavy chain 1 gene, which encodes the ATPase of the retrograde motor protein dynein, were originally r...

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Detalles Bibliográficos
Autores principales: Courchesne, Stephanie L., Pazyra-Murphy, Maria F., Lee, Daniel J., Segal, Rosalind A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035627/
https://www.ncbi.nlm.nih.gov/pubmed/21346813
http://dx.doi.org/10.1371/journal.pone.0016753

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