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Novel Allelic Variants in the Canine Cyclooxgenase-2 (Cox-2) Promoter Are Associated with Renal Dysplasia in Dogs

Renal dysplasia (RD) in dogs is a complex disease with a highly variable phenotype and mode of inheritance that does not follow a simple Mendelian pattern. Cox-2 (Cyclooxgenase-2) deficient mice have renal abnormalities and a pathology that has striking similarities to RD in dogs suggesting to us th...

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Detalles Bibliográficos
Autores principales: Whiteley, Mary H., Bell, Jerold S., Rothman, Debby A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035645/
https://www.ncbi.nlm.nih.gov/pubmed/21346820
http://dx.doi.org/10.1371/journal.pone.0016684

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