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Specific Age-Associated DNA Methylation Changes in Human Dermal Fibroblasts
Epigenetic modifications of cytosine residues in the DNA play a critical role for cellular differentiation and potentially also for aging. In mesenchymal stromal cells (MSC) from human bone marrow we have previously demonstrated age-associated methylation changes at specific CpG-sites of development...
Autores principales: | Koch, Carmen M., Suschek, Christoph V., Lin, Qiong, Bork, Simone, Goergens, Maria, Joussen, Sylvia, Pallua, Norbert, Ho, Anthony D., Zenke, Martin, Wagner, Wolfgang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035656/ https://www.ncbi.nlm.nih.gov/pubmed/21347436 http://dx.doi.org/10.1371/journal.pone.0016679 |
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