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Transcriptional Repressive H3K9 and H3K27 Methylations Contribute to DNMT1-Mediated DNA Methylation Recovery

DNA methylation and histone modifications are two major epigenetic events regulating gene expression and chromatin structure, and their alterations are linked to human carcinogenesis. DNA methylation plays an important role in tumor suppressor gene inactivation, and can be revised by DNA methylation...

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Detalles Bibliográficos
Autores principales: Wong, Chun-Ming, Wong, Carmen Chak-Lui, Ng, Yeung-Lam, Au, Sandy Leung-Kuen, Ko, Frankie Chi-Fat, Ng, Irene Oi-Lin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035659/
https://www.ncbi.nlm.nih.gov/pubmed/21347439
http://dx.doi.org/10.1371/journal.pone.0016702