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Dietary zinc supplementation of 3xTg-AD mice increases BDNF levels and prevents cognitive deficits as well as mitochondrial dysfunction
The overall effect of brain zinc (Zn(2+)) in the progression and development of Alzheimer's disease (AD) is still not completely understood. Although an excess of Zn(2+) can exacerbate the pathological features of AD, a deficit of Zn(2+) intake has also been shown to increase the volume of amyl...
Autores principales: | Corona, C, Masciopinto, F, Silvestri, E, Viscovo, A Del, Lattanzio, R, Sorda, R La, Ciavardelli, D, Goglia, F, Piantelli, M, Canzoniero, L M T, Sensi, S L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035902/ https://www.ncbi.nlm.nih.gov/pubmed/21368864 http://dx.doi.org/10.1038/cddis.2010.73 |
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