Characterization of a caspase-3-substrate kinome using an N- and C-terminally tagged protein kinase library produced by a cell-free system

Caspase-3 (CASP3) cleaves many proteins including protein kinases (PKs). Understanding the relationship(s) between CASP3 and its PK substrates is necessary to delineate the apoptosis signaling cascades that are controlled by CASP3 activity. We report herein the characterization of a CASP3-substrate...

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Detalles Bibliográficos
Autores principales: Tadokoro, D, Takahama, S, Shimizu, K, Hayashi, S, Endo, Y, Sawasaki, T
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035903/
https://www.ncbi.nlm.nih.gov/pubmed/21368862
http://dx.doi.org/10.1038/cddis.2010.65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035903/
https://www.ncbi.nlm.nih.gov/pubmed/21368862
http://dx.doi.org/10.1038/cddis.2010.65

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