Palmitoylation of human FasL modulates its cell death-inducing function

Fas ligand (FasL) is a transmembrane protein that regulates cell death in Fas-bearing cells. FasL-mediated cell death is essential for immune system homeostasis and the elimination of viral or transformed cells. Because of its potent cytotoxic activity, FasL expression at the cell surface is tightly...

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Detalles Bibliográficos
Autores principales: Guardiola-Serrano, F, Rossin, A, Cahuzac, N, Lückerath, K, Melzer, I, Mailfert, S, Marguet, D, Zörnig, M, Hueber, A-O
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035908/
https://www.ncbi.nlm.nih.gov/pubmed/21368861
http://dx.doi.org/10.1038/cddis.2010.62

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