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Knockdown of E2f1 by RNA interference impairs proliferation of rat cells in vitro

E2F1 plays a key role in cell-cycle regulation in mammals, since its transcription factor activity controls genes required for DNA synthesis and apoptosis. E2F1 deregulation is a common feature among different tumor types and can be a major cause of cell proliferation. Thus, blocking E2F1 expression...

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Detalles Bibliográficos
Autores principales:	dos Reis Vasques, Luciana, Pujiz, Regiane Simoni, Strauss, Bryan Eric, Krieger, José Eduardo
Formato:	Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2010
Materias:	Human and Medical Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036082/ https://www.ncbi.nlm.nih.gov/pubmed/21637599 http://dx.doi.org/10.1590/S1415-47572009005000104

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