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Glutathione S-transferase mu 1 (GSTM1) and theta 1 (GSTT1) genetic polymorphisms and atopic asthma in children from Southeastern Brazil

Xenobiotics can trigger degranulation of eosinophils and mast cells. In this process, the cells release several substances leading to bronchial hyperactivity, the main feature of atopic asthma (AA). GSTM1 and GSTT1 genes encode enzymes involved in the inactivation of these compounds. Both genes are...

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Detalles Bibliográficos
Autores principales:	Lima, Carmen Silvia Passos, Néri, Iramaia Angélica, Lourenço, Gustavo Jacob, Faria, Isabel Cristina Jacinto, Ribeiro, José Dirceu, Bertuzzo, Carmen Silvia
Formato:	Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2010
Materias:	Human and Medical Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036117/ https://www.ncbi.nlm.nih.gov/pubmed/21637410 http://dx.doi.org/10.1590/S1415-47572010000300007

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