Jak2 Is a Negative Regulator of Ubiquitin-Dependent Endocytosis of the Growth Hormone Receptor

BACKGROUND: Length and intensity of signal transduction via cytokine receptors is precisely regulated. Degradation of certain cytokine receptors is mediated by the ubiquitin ligase SCF(βTrCP). In several instances, Janus kinase (Jak) family members can stabilise their cognate cytokine receptors at t...

Descripción completa

Detalles Bibliográficos
Autores principales: Putters, Joyce, da Silva Almeida, Ana C., van Kerkhof, Peter, van Rossum, Agnes G. S. H., Gracanin, Ana, Strous, Ger J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036580/
https://www.ncbi.nlm.nih.gov/pubmed/21347402
http://dx.doi.org/10.1371/journal.pone.0014676

Ejemplares similares

Ejemplares similares