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Fine Mapping of Genetic Variants in BIN1, CLU, CR1 and PICALM for Association with Cerebrospinal Fluid Biomarkers for Alzheimer's Disease
Recent genome-wide association studies of Alzheimer's disease (AD) have identified variants in BIN1, CLU, CR1 and PICALM that show replicable association with risk for disease. We have thoroughly sampled common variation in these genes, genotyping 355 variants in over 600 individuals for whom m...
Autores principales: | Kauwe, John S. K., Cruchaga, Carlos, Karch, Celeste M., Sadler, Brooke, Lee, Mo, Mayo, Kevin, Latu, Wayne, Su'a, Manti, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036586/ https://www.ncbi.nlm.nih.gov/pubmed/21347408 http://dx.doi.org/10.1371/journal.pone.0015918 |
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