Clinical, genetic, and pathological features of male pseudohermaphroditism in dog

Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescen...

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Detalles Bibliográficos
Autores principales: Bigliardi, Enrico, Parma, Pietro, Peressotti, Paolo, De Lorenzi, Lisa, Wohlsein, Peter, Passeri, Benedetta, Jottini, Stefano, Cantoni, Anna Maria
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036612/
https://www.ncbi.nlm.nih.gov/pubmed/21255434
http://dx.doi.org/10.1186/1477-7827-9-12
Descripción
Sumario:Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male pseudohermaphrodite (MPH) condition.

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