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Efficient Nuclear Transport of Structurally Disturbed Cargo: Mutations in a Cargo Protein Switch Its Cognate Karyopherin

The Karyopherin (Kap) family of nuclear transport receptors enables trafficking of proteins to and from the nucleus in a precise, regulated manner. Individual members function in overlapping pathways, while simultaneously being very specific for their main cargoes. The details of this apparent contr...

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Detalles Bibliográficos
Autores principales: Chaves, Susana R., Rosenblum, Jonathan S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036716/
https://www.ncbi.nlm.nih.gov/pubmed/21347375
http://dx.doi.org/10.1371/journal.pone.0016846