Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies

ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case...

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Autores principales: Li, Dawei, He, Guang, Xu, Yifeng, Duan, Yun, Gu, Niufan, Li, Xingwang, Shi, Yongyong, Qin, Wei, Feng, Guoyin, He, Lin
Formato: Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2009
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036886/
https://www.ncbi.nlm.nih.gov/pubmed/21637446
http://dx.doi.org/10.1590/S1415-47572009005000088
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author Li, Dawei
He, Guang
Xu, Yifeng
Duan, Yun
Gu, Niufan
Li, Xingwang
Shi, Yongyong
Qin, Wei
Feng, Guoyin
He, Lin
author_facet Li, Dawei
He, Guang
Xu, Yifeng
Duan, Yun
Gu, Niufan
Li, Xingwang
Shi, Yongyong
Qin, Wei
Feng, Guoyin
He, Lin
author_sort Li, Dawei
collection PubMed
description ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case-control and family-based studies were carried out in 470 cases matched by controls, and in 532 family trios. Our results failed to show any evidence of significant association between the ERBB3 rs2292238 polymorphism and schizophrenia.
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spelling pubmed-30368862011-06-02 Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies Li, Dawei He, Guang Xu, Yifeng Duan, Yun Gu, Niufan Li, Xingwang Shi, Yongyong Qin, Wei Feng, Guoyin He, Lin Genet Mol Biol Human and Medical Genetics ERBB3 (v-erb-b2 erythroblastic leukemia viral oncogene homolog 3), encoding a receptor of neuregulin-1 (NRG1), has been considered a functional candidate gene for schizophrenia susceptibility. In order to investigate a relationship between ERBB3 gene and schizophrenia in the Chinese population, case-control and family-based studies were carried out in 470 cases matched by controls, and in 532 family trios. Our results failed to show any evidence of significant association between the ERBB3 rs2292238 polymorphism and schizophrenia. Sociedade Brasileira de Genética 2009 2009-12-01 /pmc/articles/PMC3036886/ /pubmed/21637446 http://dx.doi.org/10.1590/S1415-47572009005000088 Text en Copyright © 2009, Sociedade Brasileira de Genética. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Human and Medical Genetics
Li, Dawei
He, Guang
Xu, Yifeng
Duan, Yun
Gu, Niufan
Li, Xingwang
Shi, Yongyong
Qin, Wei
Feng, Guoyin
He, Lin
Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies
title Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies
title_full Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies
title_fullStr Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies
title_full_unstemmed Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies
title_short Schizophrenia is not associated with the ERBB3 gene in a Han Chinese population sample: Results from case-control and family-based studies
title_sort schizophrenia is not associated with the erbb3 gene in a han chinese population sample: results from case-control and family-based studies
topic Human and Medical Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036886/
https://www.ncbi.nlm.nih.gov/pubmed/21637446
http://dx.doi.org/10.1590/S1415-47572009005000088
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