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Peripheral position of CCND1 and HER-2/neu oncogenes within chromosome territories in esophageal and gastric cancers non-related to amplification and overexpression

Interphase chromosomes have been shown to occupy discrete regions of the nucleus denominated chromosome territories (CTs), their active genes being preferentially positioned on the surfaces of these CTs, where they are accessible to transcriptional machinery. By means of FISH (Fluorescence in situ H...

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Detalles Bibliográficos
Autores principales: Bizari, Lucimari, Tajara, Eloiza Helena, Silva, Ana Elizabete
Formato: Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036938/
https://www.ncbi.nlm.nih.gov/pubmed/21637674
http://dx.doi.org/10.1590/S1415-47572009005000034