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Antimony Toxicity

Antimony toxicity occurs either due to occupational exposure or during therapy. Occupational exposure may cause respiratory irritation, pneumoconiosis, antimony spots on the skin and gastrointestinal symptoms. In addition antimony trioxide is possibly carcinogenic to humans. Improvements in working...

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Detalles Bibliográficos
Autores principales: Sundar, Shyam, Chakravarty, Jaya
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037053/
https://www.ncbi.nlm.nih.gov/pubmed/21318007
http://dx.doi.org/10.3390/ijerph7124267
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author Sundar, Shyam
Chakravarty, Jaya
author_facet Sundar, Shyam
Chakravarty, Jaya
author_sort Sundar, Shyam
collection PubMed
description Antimony toxicity occurs either due to occupational exposure or during therapy. Occupational exposure may cause respiratory irritation, pneumoconiosis, antimony spots on the skin and gastrointestinal symptoms. In addition antimony trioxide is possibly carcinogenic to humans. Improvements in working conditions have remarkably decreased the incidence of antimony toxicity in the workplace. As a therapeutic, antimony has been mostly used for the treatment of leishmaniasis and schistosomiasis. The major toxic side-effects of antimonials as a result of therapy are cardiotoxicity (~9% of patients) and pancreatitis, which is seen commonly in HIV and visceral leishmaniasis co-infections. Quality control of each batch of drugs produced and regular monitoring for toxicity is required when antimonials are used therapeutically.
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spelling pubmed-30370532011-02-11 Antimony Toxicity Sundar, Shyam Chakravarty, Jaya Int J Environ Res Public Health Review Antimony toxicity occurs either due to occupational exposure or during therapy. Occupational exposure may cause respiratory irritation, pneumoconiosis, antimony spots on the skin and gastrointestinal symptoms. In addition antimony trioxide is possibly carcinogenic to humans. Improvements in working conditions have remarkably decreased the incidence of antimony toxicity in the workplace. As a therapeutic, antimony has been mostly used for the treatment of leishmaniasis and schistosomiasis. The major toxic side-effects of antimonials as a result of therapy are cardiotoxicity (~9% of patients) and pancreatitis, which is seen commonly in HIV and visceral leishmaniasis co-infections. Quality control of each batch of drugs produced and regular monitoring for toxicity is required when antimonials are used therapeutically. Molecular Diversity Preservation International (MDPI) 2010-12 2010-12-20 /pmc/articles/PMC3037053/ /pubmed/21318007 http://dx.doi.org/10.3390/ijerph7124267 Text en © 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Sundar, Shyam
Chakravarty, Jaya
Antimony Toxicity
title Antimony Toxicity
title_full Antimony Toxicity
title_fullStr Antimony Toxicity
title_full_unstemmed Antimony Toxicity
title_short Antimony Toxicity
title_sort antimony toxicity
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037053/
https://www.ncbi.nlm.nih.gov/pubmed/21318007
http://dx.doi.org/10.3390/ijerph7124267
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