Glucagon-like peptide-1 enhances cardiac L-type Ca(2+ )currents via activation of the cAMP-dependent protein kinase A pathway

BACKGROUND: Glucagon-like peptide-1 (GLP-1) is a hormone predominately synthesized and secreted by intestinal L-cells. GLP-1 modulates multiple cellular functions and its receptor agonists are now used clinically for diabetic treatment. Interestingly, preclinical and clinical evidence suggests that...

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Detalles Bibliográficos
Autores principales: Xiao, Yong-Fu, Nikolskaya, Alena, Jaye, Deborah A, Sigg, Daniel C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037307/
https://www.ncbi.nlm.nih.gov/pubmed/21251280
http://dx.doi.org/10.1186/1475-2840-10-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037307/
https://www.ncbi.nlm.nih.gov/pubmed/21251280
http://dx.doi.org/10.1186/1475-2840-10-6

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