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Glucagon-like peptide-1 enhances cardiac L-type Ca(2+ )currents via activation of the cAMP-dependent protein kinase A pathway
BACKGROUND: Glucagon-like peptide-1 (GLP-1) is a hormone predominately synthesized and secreted by intestinal L-cells. GLP-1 modulates multiple cellular functions and its receptor agonists are now used clinically for diabetic treatment. Interestingly, preclinical and clinical evidence suggests that...
Autores principales: | Xiao, Yong-Fu, Nikolskaya, Alena, Jaye, Deborah A, Sigg, Daniel C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037307/ https://www.ncbi.nlm.nih.gov/pubmed/21251280 http://dx.doi.org/10.1186/1475-2840-10-6 |
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