Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma

BACKGROUND: Arginase overexpression contributes to airways hyperresponsiveness (AHR) in asthma. Arginase expression is further augmented in cigarette smoking asthmatics, suggesting that it may be upregulated by environmental pollution. Thus, we hypothesize that arginase contributes to the exacerbati...

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Detalles Bibliográficos
Autores principales: North, Michelle L, Amatullah, Hajera, Khanna, Nivedita, Urch, Bruce, Grasemann, Hartmut, Silverman, Frances, Scott, Jeremy A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037317/
https://www.ncbi.nlm.nih.gov/pubmed/21291525
http://dx.doi.org/10.1186/1465-9921-12-19

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