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Epstein-Barr Virus Nuclear Antigen 3C Facilitates G1-S Transition by Stabilizing and Enhancing the Function of Cyclin D1

EBNA3C, one of the Epstein-Barr virus (EBV)-encoded latent antigens, is essential for primary B-cell transformation. Cyclin D1, a key regulator of G1 to S phase progression, is tightly associated and aberrantly expressed in numerous human cancers. Previously, EBNA3C was shown to bind to Cyclin D1 in...

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Detalles Bibliográficos
Autores principales:	Saha, Abhik, Halder, Sabyasachi, Upadhyay, Santosh K., Lu, Jie, Kumar, Pankaj, Murakami, Masanao, Cai, Qiliang, Robertson, Erle S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037348/ https://www.ncbi.nlm.nih.gov/pubmed/21347341 http://dx.doi.org/10.1371/journal.ppat.1001275

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