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BosR (BB0647) Controls the RpoN-RpoS Regulatory Pathway and Virulence Expression in Borrelia burgdorferi by a Novel DNA-Binding Mechanism

In Borrelia burgdorferi (Bb), the Lyme disease spirochete, the alternative σ factor σ(54) (RpoN) directly activates transcription of another alternative σ factor, σ(S) (RpoS) which, in turn, controls the expression of virulence-associated membrane lipoproteins. As is customary in σ(54)-dependent gen...

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Detalles Bibliográficos
Autores principales: Ouyang, Zhiming, Deka, Ranjit K., Norgard, Michael V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037356/
https://www.ncbi.nlm.nih.gov/pubmed/21347346
http://dx.doi.org/10.1371/journal.ppat.1001272