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Small Molecule Inhibitors of Staphylococcus aureus RnpA Alter Cellular mRNA Turnover, Exhibit Antimicrobial Activity, and Attenuate Pathogenesis

Methicillin-resistant Staphylococcus aureus is estimated to cause more U.S. deaths annually than HIV/AIDS. The emergence of hypervirulent and multidrug-resistant strains has further amplified public health concern and accentuated the need for new classes of antibiotics. RNA degradation is a required...

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Detalles Bibliográficos
Autores principales:	Olson, Patrick D., Kuechenmeister, Lisa J., Anderson, Kelsi L., Daily, Sonja, Beenken, Karen E., Roux, Christelle M., Reniere, Michelle L., Lewis, Tami L., Weiss, William J., Pulse, Mark, Nguyen, Phung, Simecka, Jerry W., Morrison, John M., Sayood, Khalid, Asojo, Oluwatoyin A., Smeltzer, Mark S., Skaar, Eric P., Dunman, Paul M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037362/ https://www.ncbi.nlm.nih.gov/pubmed/21347352 http://dx.doi.org/10.1371/journal.ppat.1001287

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