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Highly Efficient Protein Misfolding Cyclic Amplification

Protein misfolding cyclic amplification (PMCA) provides faithful replication of mammalian prions in vitro and has numerous applications in prion research. However, the low efficiency of conversion of PrP(C) into PrP(Sc) in PMCA limits the applicability of PMCA for many uses including structural stud...

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Detalles Bibliográficos
Autores principales:	Gonzalez-Montalban, Nuria, Makarava, Natallia, Ostapchenko, Valeriy G., Savtchenk, Regina, Alexeeva, Irina, Rohwer, Robert G., Baskakov, Ilia V.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037363/ https://www.ncbi.nlm.nih.gov/pubmed/21347353 http://dx.doi.org/10.1371/journal.ppat.1001277

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