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De-Novo Discovery of Differentially Abundant Transcription Factor Binding Sites Including Their Positional Preference

Transcription factors are a main component of gene regulation as they activate or repress gene expression by binding to specific binding sites in promoters. The de-novo discovery of transcription factor binding sites in target regions obtained by wet-lab experiments is a challenging problem in compu...

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Detalles Bibliográficos
Autores principales: Keilwagen, Jens, Grau, Jan, Paponov, Ivan A., Posch, Stefan, Strickert, Marc, Grosse, Ivo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037384/
https://www.ncbi.nlm.nih.gov/pubmed/21347314
http://dx.doi.org/10.1371/journal.pcbi.1001070