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De-Novo Discovery of Differentially Abundant Transcription Factor Binding Sites Including Their Positional Preference
Transcription factors are a main component of gene regulation as they activate or repress gene expression by binding to specific binding sites in promoters. The de-novo discovery of transcription factor binding sites in target regions obtained by wet-lab experiments is a challenging problem in compu...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037384/ https://www.ncbi.nlm.nih.gov/pubmed/21347314 http://dx.doi.org/10.1371/journal.pcbi.1001070 |