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Serine residue 115 of MAPK-activated protein kinase MK5 is crucial for its PKA-regulated nuclear export and biological function

The mitogen-activated protein kinase-activated protein kinase-5 (MK5) resides predominantly in the nucleus of resting cells, but p38(MAPK), extracellular signal-regulated kinases-3 and -4 (ERK3 and ERK4), and protein kinase A (PKA) induce nucleocytoplasmic redistribution of MK5. The mechanism by whi...

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Detalles Bibliográficos
Autores principales:	Kostenko, Sergiy, Shiryaev, Alexey, Gerits, Nancy, Dumitriu, Gianina, Klenow, Helle, Johannessen, Mona, Moens, Ugo
Formato:	Texto
Lenguaje:	English
Publicado:	SP Birkhäuser Verlag Basel 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037495/ https://www.ncbi.nlm.nih.gov/pubmed/20734105 http://dx.doi.org/10.1007/s00018-010-0496-2

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