A B2 SINE insertion in the Comt1 gene (Comt1(B2i)) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains

Catechol-O-methyltransferase (COMT) is a key enzyme for dopamine catabolism and COMT is a candidate gene for human psychiatric disorders. In mouse it is located on chromosome 16 in a large genomic region of extremely low variation among the classical inbred strains, with no confirmed single nucleoti...

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Detalles Bibliográficos
Autores principales: Kember, R L, Fernandes, C, Tunbridge, E M, Liu, L, Payá-Cano, J L, Parsons, M J, Schalkwyk, L C
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037563/
https://www.ncbi.nlm.nih.gov/pubmed/20618449
http://dx.doi.org/10.1111/j.1601-183X.2010.00614.x

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