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Cross-Crystal Averaging with Search Models to Improve Molecular Replacement Phases
The application of molecular replacement (MR) in macromolecular crystallography can be limited by the “model bias” problem. Here we propose a strategy to reduce model bias when only part of a new structure is known: after the MR search, structure determination of the unknown part of the new structur...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037595/ https://www.ncbi.nlm.nih.gov/pubmed/21300285 http://dx.doi.org/10.1016/j.str.2010.12.007 |