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Proteasome-independent Degradation of Canonical NFκB Complex Components by the NleC Protein of Pathogenic Escherichia coli

The NFκB transcription factor is a key component of immune and inflammatory signaling as its activation induces the expression of antimicrobial reagents, chemokines, cytokines, and anti-apoptotic factors. Many pathogens encode effector proteins that target factors regulating NFκB activity and can pr...

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Detalles Bibliográficos
Autores principales:	Mühlen, Sabrina, Ruchaud-Sparagano, Marie-Hélène, Kenny, Brendan
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037621/ https://www.ncbi.nlm.nih.gov/pubmed/21148319 http://dx.doi.org/10.1074/jbc.M110.172254

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