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Dkk1 Regulates Ventral Midbrain Dopaminergic Differentiation and Morphogenesis
Dickkopf1 (Dkk1) is a Wnt/β-catenin inhibitor that participates in many processes during embryonic development. One of its roles during embryogenesis is to induce head formation, since Dkk1-null mice lack head structures anterior to midbrain. The Wnt/β-catenin pathway is also known to regulate diffe...
Autores principales: | Ribeiro, Diogo, Ellwanger, Kristina, Glagow, Désirée, Theofilopoulos, Spyridon, Corsini, Nina S., Martin-Villalba, Ana, Niehrs, Christof, Arenas, Ernest |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037958/ https://www.ncbi.nlm.nih.gov/pubmed/21347250 http://dx.doi.org/10.1371/journal.pone.0015786 |
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