Ab-Externo AAV-Mediated Gene Delivery to the Suprachoroidal Space Using a 250 Micron Flexible Microcatheter

BACKGROUND: The current method of delivering gene replacement to the posterior segment of the eye involves a three-port pars plana vitrectomy followed by injection of the agent through a 37-gauge cannula, which is potentially wrought with retinal complications. In this paper we investigate the safet...

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Detalles Bibliográficos
Autores principales: Peden, Marc C., Min, Jeff, Meyers, Craig, Lukowski, Zachary, Li, Qiuhong, Boye, Sanford L., Levine, Monica, Hauswirth, William W., Ratnakaram, Ramakrishna, Dawson, William, Smith, Wesley C., Sherwood, Mark B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037961/
https://www.ncbi.nlm.nih.gov/pubmed/21347253
http://dx.doi.org/10.1371/journal.pone.0017140

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